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Open Journal of Hematology

ISSN: 2075-907X
Volume 8, 2017



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Open Journal of Hematology, 2017, 8-2 [Mini Review]

Genomic markers associated with insulin resistance and Type 2 Diabetes in African Americans: A review

Crystal Heath Dodson, Lisa Maness

School of Nursing, College of Health and Human Services, University of North Carolina, USA

Corresponding Author & Address:

Crystal Heath Dodson*
School of Nursing, College of Health and Human Services, University of North Carolina at Wilmington, McNeill Hall 3030, USA; Phone: (336) 962-7877; Email: dodsonc@uncw.edu

Article History:
Published: 2nd March, 2017   Accepted: 2nd March, 2017
Received: 10th January, 2017  

© Dodson et al.; licensee Ross Science Publishers

ROSS Open Access articles will be distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work will always be cited properly.

Keywords: Genomics, biomarkers, diabetes, African ancestry, genomic markers

Abstract:

Purpose: Personalized medicine is exponentially advancing.  In order to optimize an individual's healthcare, their individual genetic makeup, as well as environmental profiles, need to be quantified. The prevalence of type 2 diabetes among African Ancestry is alarmingly high within northwester North Carolina, with preliminary studies indicating that levels are even higher than the general U.S. population. Our overall goal is to identify genetic markers that are linked to type 2 diabetes and insulin resistance within this population.

Materials and Methods: A literature review was conducted to determine which genomic markers have been associated with type 2 diabetes and insulin resistance with the African population.

Results and Conclusions: Thirteen studies reported genomic markers that have been associated with type 2 diabetes within the African Ancestry. A compilation of these genomic markers are presented within this review.



©2017 Ross Science Publishers