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Open Journal of Hematology

ISSN: 2075-907X
Volume 8, 2017

Indexed in:

Open Journal of Hematology, 2014, 5-6 [Case Report]

Hypofibrinogenemia Complicating Pregnancy Case Report and Review of Literature

Thevoor V. Chitra*, Seetha Panicker

Department of Obstetrics and Gynecology, PSG Institute of Medical Sciences & Research, Coimbatore-641004

Corresponding Author & Address:

Thevoor V. Chitra*
Department of Obstetrics and Gynecology, PSG Institute of Medical Sciences & Research, Coimbatore-641004; Email: chitravi@vsnl.com; Mobile: 0-94433 53191; Office Phone: 91-422- 4345130

Article History:
Published: 25th August, 2014   Accepted: 25th August, 2014
Received: 18th June, 2014   Revised: 25th July, 2014

© Chitra et al.; licensee Ross Science Publishers

ROSS Open Access articles will be distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work will always be cited properly.

Keywords: Hypofibrinogenemia, dysfibrinogenemia, fibrinogenconcentrate, fibrinogen replacement therapy, abortion, abruption


Congenital fibrinogen disorder may be either afibrinogenemia / hypofibrinogenemia / dysfibrinogenemia. Afibrinogenemia may present at birth as bleeding from umbilical cord. Patients with hypofibrinogenemia may present only during surgical intervention or during pregnancy. Pregnancy with this condition is associated with a very high incidence of abortion & abruption. Fibrinogen replacement can be done using either cryoprecipitate or fibrinogen concentrate. Successful pregnancies have been reported using cryoprecipitate & fibrinogen concentrate (FC). We report a woman with 6 abortions previously who was treated with fibrinogen replacement therapy & delivered a live child.

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