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Open Journal of Hematology

ISSN: 2075-907X
Volume 8, 2017



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EMBASE

Open Journal of Hematology, 2013, 4-1 [Short Communication Research]

Orthopaedic Status and Surgical Needs of Patients with Haemophilia in Algeria

Yasmina Berkouk-Redjimi*, Yasmina Ouarlent, Selma Hamdi, Hadj Touhami§, Naima Mesli, Fatiha Grifi**, Zahia Zouaoui††, Meriem Belhani*

* Haematology Department, University Hospital Beni Messous Algiers
Haematology Department, University Hospital Batna
Haematology Department, University Hospital Sétif
§ Haematology Department, University Hospital Oran
Haematology Department, University Hospital Tlemcen
** Haematology Department, University Hopital Annaba
†† Haematology Department, University Hospital Sidi Belabes

Corresponding Author & Address:

Yasmina Berkouk-Redjimi*
Haematology Department, University Hospital Beni Messous, Issad Hassani, Algiers, Algeria 16000; Tel/fax: +213 21931186;
Email: redjimiberkouk@hotmail.com

Article History:
Published: 22nd January, 2013   Accepted: 22nd January, 2013
Received: 27th December, 2012      

© Berkouk-Redjimi et al.; licensee Ross Science Publishers

ROSS Open Access articles will be distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work will always be cited properly.

Keywords: Algeria, costs, haemophilia, joint disease, orthopaedic, surgery, prophylaxis

Abstract:

Despite the availability of factor replacement to manage acute bleeding in haemophilia, haemarthrosis may occur due to delayed therapy or lack of detection, leading to joint damage. Orthopaedic surgery is one option to help improve patient quality of life. Assessment of current treatment patterns is required for physicians to optimize long-term management of patients; however, there are few studies available to determine the real-life situation in African/Middle-Eastern countries, such as Algeria.

This was a multicentre, retrospective study of patients with haemophilia treated with on-demand factor replacement. Seven haematology centres in Algeria provided evaluable clinical data for 536 patients, including joint status and requirement for surgical intervention.

Surgery was recommended in 326 (61%) patients (239 patients with severe haemophilia, 79 moderate and eight mild). Surgical procedures per patient age group were: 11 in patients ≤5 years, 34 in 6–10 years, 169 in 11–20 years, 183 in 21–30 years and 122 in ≥31 years. 14% of all procedures involved joint replacement, 56% other major surgeries and 30% minor surgeries (synoviorthesis). Minor surgery was most common in younger patients, while major surgeries increased proportionately with patient age.

In Algeria, insufficient use of factor replacement has led to many patients with haemophilia experiencing haemarthrosis, leading to joint damage requiring surgery. This study aids assessment of the scale of the problem and identification of the surgical needs of patients. This may help plan targeted resourcing for patients most at risk of long-term disability and those likely to benefit from earlier surgical intervention.



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